IMRAN KHANAssistant Professor
Biotechnology
,
Garden
Campus
Contact Information:
imrankhan31@awkum.edu.pk Assistant Professor (at Abdul Wali Khan University Mardan) 16 Aug 2022 -Continue Assistant Professor (at University of Malaysia Sabah) 11 May 2022 – 15 Aug 2022 At University of Malaysia, Dr. Khan was required to allocate 30% of his time to teaching and 70% to research. At this point time, he planned to explore the anti-obesogenic effects of natural compounds in pre-clinical animal models. He prospected to investigate the anti-cancer properties of various bio-active natural compounds. Post-doctoral Fellow (Under Global Talent Program by Macau Government) Sep 2019 – Aug 2021 Dr. Khan was awarded fellowship under the global talent program by Macau government. He joined Prof. Wendy’s lab which was determining the peanut allergy causes at microbial level. He contributed to the development of a pre-clinical model for peanut allergy. Through 16S amplicon sequencing and modern culturomics techniques, he identified a single bacterium that was the main culprit behind peanut allergy development. Through heuristic wet and dry lab experiments, he also contributed to determine one herbal compound and two potential probiotic bacterial species that alleviated anaphylactic symptoms in the mouse model. In addition, he was engaged in another project that was focused to examine the anti-aging properties of icariin (an herbal compound) at the interface of gut microbiome. Besides, he was collaborating with other colleagues by mining BIG DATA for identifying potential clinical markers as a target for drug and diagnostics. Post-doctoral Fellow (Supported by FDCT of Macau Government) Jul 2016 – Aug 2019 Dr. Khan was hired by Prof. Wendy to determine the microbial causes in colorectal cancer development and progression, where he profiled microbiome composition of different knock out mouse model for cancer (APCMin/+, KRAS, P53). He helped in screening various herbal compounds and other TCM formulae to fix the dysbiotic gut microbial composition. He identified several polysaccharides, ginsenosides, flavonoids, and saponins that possessed the ability to fix the disturbed microbial composition and resulted in lowering polyp burden in pre-clinical mouse model. Research Associate (Employer NIBGE, PIEAS, Pakistan) Mar – Nov 2011 He was selected as a Research Associate at the National Institute for Biotechnology and Genetic Engineering, PIEAS, Pakistan. He was stationed in the Industrial Biotechnology Division and was tasked to develop mutant fungal strains for mass-level enzyme production for industrial application. |